What are the most common side effects of cisplatin and etoposide?
COMMON, SOME MAY BE SERIOUS
- Infection, especially when white blood cell count is low.
- Anemia which may require blood transfusions.
- Bruising, bleeding.
- Kidney damage which may cause swelling, may require dialysis.
- Hearing loss including ringing in ears.
- Hair loss.
- Sores in mouth which may cause difficulty swallowing.
Do you give cisplatin before etoposide?
Typically, these two drugs are given one after the other on the same day. Cisplatin + Etoposide are usually given at an outpatient infusion center, allowing the person to go home afterwards.
What are the side effects of cisplatin and pemetrexed?
In clinical studies, the most commonly reported side effects with cisplatin + pemetrexed are shown here….Side Effects
- Low white blood cells [neutropenia]
- Hair loss.
- Nausea.
- Fatigue.
- Vomiting.
- Anemia [low red blood cells] (6%)
- Increased bleeding risk [Low platelets]
What is the adverse effect of etoposide?
Nausea, vomiting, diarrhea, dizziness, tiredness, weakness, changes in taste, loss of appetite, and pain/redness at the injection site may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting.
Why does cisplatin cause side effects?
Cisplatin is an irritant. An irritant is a chemical that can cause inflammation of the vein through which it is given. If cisplatin escapes from the vein it can cause tissue damage.
What is cisplatin and etoposide?
What is etoposide and cisplatin? Etoposide and cisplatin chemotherapy (EP) is a combination chemotherapy treatment used to treat different types of cancer. It is best to read this information with our general information about chemotherapy and the type of cancer you have.
What is etoposide and cisplatin?
What are the side effects of cisplatin?
Side Effects
- Black, tarry stools.
- blood in urine or stools.
- burning, numbness, tingling, or painful sensations.
- change in frequency of urination or amount of urine.
- cough or hoarseness.
- difficulty in breathing.
- feeling of fullness in the ears.
- fever or chills.
How long does chemo stay in your body?
Chemotherapy can be administered a number of ways but common ways include orally and intravenously. The chemotherapy itself stays in the body within 2 -3 days of treatment but there are short-term and long-term side effects that patients may experience.
What are the long term effects of cisplatin?
Cisplatin (CDDP) is a frequently employed chemotherapeutic drug both in curative and palliative settings. When cancer patients are cured due to CDDP therapy, they unfortunately often experience severe long‐term side effects including irreversible hearing loss (ototoxicity) and permanent neuronal and renal damage.
Will I lose my hair on etoposide?
This medicine often causes a temporary loss of hair. After treatment with etoposide has ended, normal hair growth should return.
When does cisplatin side effects start?
Nausea and vomiting usually begin within 1 to 4 hours after treatment and last up to 24 hours. Various degrees of vomiting, nausea and/or anorexia may persist for up to 1 week after treatment.
Does cisplatin cause ototoxicity?
Cumulative renal toxicity associated with Cisplatin is severe. Other major dose-related toxicities are myelosuppression, nausea, and vomiting. Ototoxicity, which may be more pronounced in children, and is manifested by tinnitus, and/or loss of high frequency hearing and occasionally deafness, is significant.
Will you have hair loss with cisplatin?
Hair loss can be caused for many reasons including stress, chemotherapy (cisplatin) and for dietary reasons. Cisplatin can cause some hair loss but this is uncommon, especially a few months after treatment. It may be helpful to talk over your hair loss with your oncologist/GP.
Does cisplatin cause blood clots?
Who have Blood clot in the legs with Cisplatin – from FDA reports. Blood clot in the legs is found among people who take Cisplatin, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Etoposide, and have Transitional cell carcinoma.
Can cisplatin cause nephrotoxicity?
Cisplatin for injectioncan cause dose-related nephrotoxicity, including acute renal failure that becomes more prolonged and severe with repeated courses of the drug. Renal toxicity typically begins during the second week after a dose ofCisplatin for injection.
